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29-Jun-2017 17:08

We aimed to investigate the effects of EMT on Cisplatin resistance in HNSCC (head and neck squamous cell carcinoma)-cells.

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Aim: The objective of this study was to identify candidate proteins and the main signaling pathways involved in Ca P radioresistance, validate the identified potential biomarkers in Ca P-radioresistant (RR) cell lines and animal xenografts, and perform the functional study from a selected candidate.Seelsorge und klinische Sozialarbeit gehören ebenfalls zum Behandlungsteam.In unserer Klinik finden Menschen mit In unserer Psychiatrischen Institutsambulanz (PIA) finden allgemeine, offene und Spezialsprechstunden einschließlich neuropsychologischer und ADHS-Diagnostik (Aufmerksamkeitsdefizit- und Hyperaktivitätsstörung) statt.Our findings indicate that interfering EMT/CSCs, ALDOA and signaling pathways, in combination with RT is promising for Ca P radiotherapy.

Aim: EMT contributes to tumor progression and metastasis.Results: A total of 309 signaling pathway proteins were identified to be significantly different between Ca P and Ca P-RR cells (P ≤ 0.05, fold differences 80% power).